Based on something I read in another search, Windows 10 does allow for different brand GPU's to used at one time. In the 4th PCIe x 16 slot I have a ASUS GT640-DCSL-2GD3 gpu that I have 3 of the Dell monitors hooked up to and it is working fine. I am using Windows 10 Pro 64 bit operating system. I get the same thing if I try to enable the 4th monitor in Windows 7 display settings (just gives me an 'Unable to save display settings' error). If I try to extend to it, FirePro software gives me a message that I have to disable one other monitor before I can enable that one. I did check the device manager but the second AMD Firepro W4100 did not show up. The AMD FirePro software shows a 4th monitor as disabled. I could not get the second AMD Firepro W4100 to be recognized in either PCIe slot #2 or #3. ![]() So I unplugged two monitors from the first AMD Firepro W4100 in slot #1 that where working and hooked up two of the active adapters that I was trying to use on the second AMD Firepro W4100 in slot #2 to the working AMD Firepro W4100 in slot #1 and they worked fine, so that eliminates the adapter, cable and monitor being bad. I then tried it in PCIe x 16 slot #3 and it still did not work. However when I went to install the second AMD Firepro W4100 into PCIe x 16 slot #2 it did not work. I installed the first AMD Firepro W4100 into PCIe x 16 slot #1 and it works fine. ![]() I have 8 active mini displayport to DVI adapters for my DVI cables made by Tripp Lite # P137-06N-DVI-V2. I am trying to hook up 10 Dell 2001 FP monitors. In this computer I have an Intel i7-4820K cpu and 32 GB's of DDR 3.0 RAM at 1600 ghz. I have a ASUS X79 Deluxe motherboard that has 4 PCIe X 16 slots.
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